Information You Need To Know

Diet- Drug Interaction

Dear Patient

You must know if you need to take your medicine before with or after your meal as food may affect the absorption of medication or produce unwanted reactions that can have negative impact on your health or prevent your body from optimal benefit of the medication.

You will sometimes be required to avoid certain food or drink or to ingest some when you are taking certain medication.

Therefore you are advised to consult your treating doctor. Here some examples of the effects of drugs on nutrient absorption:

The effects of drugs on nutrient absorption

Vitamins: prolonged antibiotic therapy may decrease vitamin K synthesis. Laxtives and cholestyramine resin in large doses may decrease absorption of fat soluble vitamins.

Minerals: calcium and magnesium preparations may inhibit absorption of iron, phosphate, and fluoride. Ethanol promotes renal magnesium excretions. Steroids may decrease calcium utilization. Some steroids cause sodium and fluid retention and potassium loss. Aspirin may decrease sodium and chloride excretion.

Protein: some steroids, therapeutic doses of salicylates, and some anti biotics may induce negative nitrogen balance that cannot always be offset by a high calorie, high protein diet.

Carbohydrate: some cathartics increase gastrointestinal motility, decreasing glucose absorption.

Fat: surfactants, some antibiotics (such as tetracycline), some hypocholesterolemic drugs, and some cathartics may decrease fat absorption.

Foods are generally digested better if drugs are administered with food or after meals (when the nature of the drug permits).